I’ve Asked the Experts—These Are the Best Peptide Skincare Products For Healthy, Plump Skin

This award-winning peptide product has a whole host of other amazing ingredients too – Swiss apple stem cell extract minimises the look of fine line and wrinkles, and squalene deeply hydrates. There’s also an eyeseryl and argireline complex that targets dark circles and puffiness.

Pros: This light, hydrating gel is so cooling and can be used on your whole eye area.

Cons: It’s pretty much love at first sight with this one.

Customer Review: “This eye cream really works on wrinkles and dark circles, while being suitable for super-sensitive eyes & skin.”

Don’t forget your lips when it comes to your skin care. This peptide lip treatment deeply nourishes and replenishes dry lips, whilst also plumping them with hydration. There’s the peptides that work longer term in keeping your lip structure full and smooth, shea butter to moisturise, cupaçu to boost skin suppleness and maintain elasticity, and babassu to support the skin microbiome and replenish moisture.

Pros: Doubles up as a lip gloss as it gives you the shiniest, plump lips.

Cons: This is a cult product from Hailey Bieber’s brand, so certain colours are often sold out.

Customer Review: “I love this lip treatment because it really feels like it penetrates into the skin on my lips and makes it better. Other lip balms only sit on the top layer of my lips, and then when I eat, drink, or dab my lips with a napkin, it’s gone and my lips feel dry and scaly. But not with this lip product. I love it so much, I ended up getting it in a range of colours. I am hooked!”

This serum has a powerful combination of peptides and vegan stem cells, to accelerate cellular turnover, boosting collagen and minimising the appearance of deep wrinkles.

Pros: I actually use this on my neck as it has a perfect-for-this rollerball applicator. It really firms and tightens, and is so light and cooling.

Cons: It is a pricey option, but it is designed to give clinical results at home and comes with cutting edge science and 20 years of skin clinic expertise.

Customer Review: “Already a fan of Kate Somerville and as of this year, I have started to have my own concerns of fine lines and wrinkles (especially around my eyes/under the brow, and smile lines). Not only is this super easy to use, as the metal applicator is built into the product, but this makes lazy-girl-me more willing to grab this (not to mention, it feels cool and lovely to use). I have noticed my skin appears more plump the morning after using this and therefore I would definitely recommend!”

As well as the firming and lifting peptides, there’s also a host of other ingredients in this serum that target other signs of ageing and skin damage, such as 3% sh-Oligopeptide-1 Growth Factor (GF) Complex – a powerful active that repairs skin and strengthens the skin barrier. This serum is designed to visibly reduce even the most stubborn wrinkles and fine lines, with ingredients such as its copper lysinate.

Pros: It focusses on repairing and strengthening the skin as well as lifting, firming and minimising lines and wrinkles.

Cons: It is a very expensive option but does a multitude of things.

Customer Review: “I’ve been using this for 2 weeks now. Seen overall improvement on my crows feet and my skin appears brighter and firmer. I’ve also received compliments from friends that skin is looking radiant.”

This deeply hydrating serum contains the collagen-boosting Matrixyl 3000™ peptide, which plumps and firms skin, and decreases the appearance of line and wrinkles. There’s also a Syn-Tacks™ Dual peptide to further support this.

Pros: An affordable option available on the high street.

Cons: It doesn’t have any other fancy ingredients or benefits like the more expensive options have.

Customer Review: “I’m convinced this has helped with my deep line between my eyebrows! My skin looks much plumper! I have been using for about 6 months now with no sensitive issues.”

This peptide complex serum gives both immediate results and lasting results after 4 weeks. It contains 6 different pro-collagen peptides to target multiple layers of the skin. There’s also immediately hydrating and skin plumping hyaluronic acid and glycerin.

Pros: Clinically proven to give a remarkably younger appearance overall, dramatically diminished appearance of wrinkle depth & volume and reduced crow’s feet within 28 days.

Cons: There aren’t any. Paula’s Choice are a leading, completely transparent skincare brand.

Customer Review: “I loved this from the first time I tried it and am now on my second bottle. It really does give my skin a boost and is now a priority in my skincare route. Another great find from this superb brand!”

This powerhouse contains 8 peptides and 8 amino acids, which all boost collagen in the skin to increase firmness and elasticity over time. Amino acids also greatly increase skin hydration. The 3 ceramides in the formula moisturise and fortify the skin barrier, and hyaluronic acid hydrates.

Pros: The texture of this is divine and it sinks into the skin.

Cons: Sorry, but the ingredient line-up is great. Definitely a top choice of moisturiser.

Customer Review: “This moisturiser leaves my skin hydrated and plump looking. I love it! Packed with peptides, ceramides and collagen, it is perfect for my perimenopausal skin.”

This peptide overnight cream for the face and neck deeply hydrates and restores the skin’s moisture barrier, calms sensitivity, and reduces the appearance of lines and wrinkles. The skin has its own natural nightly renewal process, which makes it the perfect time for the cream’s peptides to come into play.

Pros: Supports the skin barrier to keep moisture locked in.

Cons: Again, this is a pricey option, but comes with a lot of scientific backing.

Customer Review: “My skin is so radiant since using this product and I’ve noticed a reduction in the wrinkles on my forehead and around my eyes! This is definitely one of my favourite products from Clinique.”

This light peptide moisturiser also has ceramides to moisturise and strengthen your skin barrier to keep that moisture where you need it and defend against environmental aggressors. There’s also niacinamide to minimise dark spots and refine skin texture, and centella asiatica to soothe irritated skin. Hyaluronic acid, glycerin and squalane hydrate.

Pros: This is fragrance-free and skin barrier fortifying with lots of soothing ingredients, making it ideal for sensitive skin.

Cons: It’s doesn’t feel luxurious to apply and the packaging is basic.

Customer Review: “I am a combination but a little towards the drier side these days and this cream was an instant quench of thirst. Suddenly my tired skin looked renewed and supple for the whole day/night after one use. The cream is rich and will give you that lovely cushiony feel without being sticky or feeling overly heavy.

My skin is flooded with the hydration it needs, looks so healthy, and feels so plump. I am obsessed with the dewy glow it gives the skin and the almost blurred finish. If you are looking for something that feels like a nice comfy blanket on the skin, this is going to be your favourite cream.”

This potent serum contains Hexapeptide and Dipeptide to improve the appearance of lines and wrinkles. It’s scientifically proven to reduce the appearance of 9 types of contraction lines. There’s also 5% PHA to exfoliate the skin to improve skin texture and radiance. The serum also contains pore-refining niacinamide, and laminaria extract to hydrate and soothe skin.

Pros: It contains a combination of different peptides. Dr Emma Craythorne from Skinceuticals says that “SkinCeuticals P-Tiox is a combination of peptides, and these peptides have been shown to work to reduce contraction lines and give a more glass like appearance on the skin. The two peptides work together in synergy.”

Cons: It’s the most expensive of all the products here.

Customer Review: “I’ve been using SkinCeuticals P-TIOX Serum for a while now, and I’m really impressed with the results. The serum has a light, watery texture that absorbs quickly without leaving my skin feeling greasy. I love how easy it is to layer with other products in my routine, whether it’s in the morning or evening. One of the main reasons I love this product is its powerful antioxidant blend. I feel like it’s helping to protect my skin from daily damage caused by pollution and UV rays. Over time, I’ve noticed my skin looking brighter and smoother, and the fine lines I had seem less noticeable. I think it’s worth the investment because I can see the long-term benefits. It’s especially good for those who want to prevent early signs of aging and keep their skin looking healthy. Overall, I’m really happy with this serum and would recommend it to anyone looking for a high-quality, antioxidant-rich product!”